A mysterious woman resurfaces in 2036 New York City with no memory of the past 40 years and powers she cannot explain. As PDNY detective Martin O'Reilly begins tracking her, a separate thread emerges: others like her are appearing across the city, each with abilities tied to a pattern of disappearances stretching back decades. When a third post-human surfaces in Brooklyn, the three reluctantly unite and trace every thread back to a single corporation. By season's end, the conspiracy runs deeper than any of them expected and the cost of pulling at it is permanent.